Antibiotic Class as High Priority:
As part of its expert evaluation, ANSES has created a pioneering a list identifying specific bacterium/antibiotic class combinations that necessitate priority monitoring in animals due to their significant impact on human health. This list is formulated based on three critical health criteria: the transmissibility of antimicrobial resistance, the availability of alternative antibiotics, and the incidence of infections and deaths linked to these bacteria.
Among the 11 combinations included, five have been categorized as high priority:
1. **Enterobacterales/carbapenems**
2. **Enterobacterales/third- and fourth-generation cephalosporins**
3. **Staphylococcus aureus/methicillin**
4. **Enterobacterales/fluoroquinolones**
5. **Enterobacterales/polymyxins**
If a resistant bacterium belonging to any of these high-priority classes is identified in a livestock animal or pet during treatment, the Agency advises conducting genome sequencing. This initiative aims to evaluate and quantify the extent to which these animal reservoirs may contribute to the transmission of resistant bacteria to humans.
