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Webinar: Understanding Canine Leptospirosis: A Means of Protecting Your Pets and Your Family

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A free online class brought to you by Bioguard

Leptospira infections in dogs and how to keep yourself and your furry friend healthy and safe!

Access to the on-demand recording is FREE
Obtain a CERTIFICATE of attendance



Leptospirosis is a bacterial infectious disease that affects dogs and pet owners. The clinical signs of the infection can range from mild, subclinical symptoms to more severe conditions like acute kidney injury, hepatopathy, respiratory disease, or even death. Given that it's a zoonotic disease, it's important for medical professionals to remain vigilant and knowledgeable about the different clinical presentations of leptospirosis.

In this lecture, we'll explore the various strains of Leptospira that can cause leptospirosis and the diagnosis and treatment options available for dogs. Additionally, we'll delve into the prevention measures and challenges associated with vaccinating dogs against this disease.


Dr. Sushant obtained his Ph.D. from National Tsing Hua University and Academia Sinica, Taiwan. He has expertise in biomarker discovery and protein structural biology with a strong research background in investigating potential biomarkers for target diseases. Currently, Dr. Sushant works as a diagnostic specialist with Bioguard Corporation (Taiwan).

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Sep. 27

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8 PM – 9 PM

Taipei Local Time

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Certificate of Attendance

eCertificate will be issued to the registered attendants joining the webinar for at least 50 minutes.

How to Join: Three Options:

Option 1: Watch via ZOOM

You can join us live directly via Zoom by simply registering. Please note that we will send you the link that is unique to you and should not be shared with anyone.

Option 2: Watch on our FACEBOOK Page

Follow our Facebook page and join us live during the webinar.

Option 3: Watch at your LEISURE

Registering to attend this webinar will also gain you access to the on-demand recording, which will be available 24 hours later.


We look forward to seeing you at this event.

Happy Learning!

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Leptospirosis in Dogs

Leptospirosis is a bacterial infection that affects many mammals, including dogs and humans. Although cats are generally resistant, leptospirosis can still be transmitted to humans, making it a zoonotic disease. Leptospirosis is mainly caused by Leptospira canicola and Leptospira icterohaemorrhagiae. However, recent evidence indicates exposure to a wider range of serogroups, such as Leptospira grippotyphosa, Leptospira australis, and Leptospira sejroe.


Leptospires are primarily spread through the urine of reservoir hosts, which typically do not exhibit clinical signs. The bacteria can persist in the renal tubules for a long time, leading to ongoing environmental contamination. Incidental hosts can also become infected through direct contact with mucous membranes or damaged skin. More commonly, infection occurs indirectly through contact with soil or surface water contaminated with urine from infected animals, such as rodents, foxes, hedgehogs, or other dogs. Dogs in rural environments with access to rivers or lakes are at higher risk.

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Clinical signs

• Pyrexia

• Vomiting, diarrhoea, altered appetite, abdominal pain

• Shivering; muscle pain or weakness

• Dehydration, oliguria, anuria (sometimes polyuria or polydipsia)

• Shock, tachycardia, arrhythmias

• Lethargy

• Bleeding disorders

• Coughing, dyspnoea or tachypnoea (rhinitis, tonsillitis in some cases)

• Icterus, hepatic encephalopathy

• Conjunctivitis, scleral injection, erythematous, bullous lesions, uveitis (which can be delayed for many weeks to months)


The microscopic agglutination test (MAT) detects the presence of antibodies against Leptospira in a dog's blood. If the level of antibodies (called a titer) is high enough or can be shown to rise over time, then infection is confirmed. Other serology tests, such as ELISA or rapid test, are also applied to the detection of antibodies against Leptospira in a dog's blood.

Many molecular assays, including real-time PCR, have been developed that detect pathogenic Leptospira DNA in clinical specimens. Detection of leptospiral nucleic acid in blood or tissues is diagnostic for infection, while detection in kidney tissue or urine is consistent with either infection or colonization.

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• To treat an infection, Doxycycline can be given at a dose of 5 mg/kg every 12 hours or 10 mg/kg every 24 hours for a period of 14 days.

• In patients with gastrointestinal symptoms, an intravenous penicillin derivative can be used initially. This may include a dose of 20 to 30 mg/kg of ampicillin given every six to eight hours, 20 to 30 mg/kg of amoxicillin given every six to eight hours, or 25,000 to 40,000 u/kg of penicillin given every six to eight hours.


•Vaccination; bivalent vaccines that include serogroups L icterohaemorrhagiae and L canicola are recommended.

• Education; veterinarians should inform pet owners about ways to prevent reinfection by limiting access to potential sources of infection such as external water sources and wildlife carriers.


Bioguard’s Qmini PCR can detect Leptospira spp. DNA in 90 minutes at your clinics using EDTA-blood or urine as samples.

To learn more about Qmini PCR, click here
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Achieving optimal outcomes through exceptional performance is a priority in any field, particularly in veterinary medicine. Thanks to advanced nucleic acid extraction technology and PCR TaqMan probe, our testing methodology provides unparalleled sensitivity and accuracy, enabling early detection of potentially infectious diseases and reducing the risk of further complications. This approach aids veterinarians in promptly treating unhealthy animals, ultimately leading to better health outcomes for our animal companions.

For any direct inquiries, please contact us at: [email protected]

About Bioguard Corporation

The Bioguard is a company focusing on animal disease diagnostic services and products.
Our animal health diagnostic center is the first and only ISO/ IEC 17025 accredited animal disease testing laboratory in Taiwan and China.

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